Description
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Product name
Tertiapin Q, blocker of inward-rectifier r K+ channels -
Description
Potent inward rectifier K+ channel blocker -
Biological description
Potent blocker of inward rectifier K+ channels. Stable analog of the bee venom tertiapin. High affinity for ROMK1 and GIRK1/4 (Ki values are 1.3 and 13.3 nM, respectively). -
Purity
> 95% -
CAS Number
252198-49-5 - Molecular Formula: C106H175N35O24S4
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Chemical structure
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References
1. Drici, M.D. et al. (2000) Br. J. Pharmacol. 131, 569.
2. mura, H. et al. (2000) J. Pharmacol. Exp. Ther. 293, 196.
3. Peleg, S. et al. (2002) Neuron 33, 87.