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GMP Monoclonal Anti-Human CD3 Antibody (OKT3) DMF Filed

Product specifications

CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.

Catalog Number

GMP-MC0323

Product Category

Cell Therapy Antibodies

Material Category

Cell Therapy Antibodies

Storage Tempreture

-70℃

Species

Mouse

Host

HEK293

Target of Antibodies

CD3

Format

Liquid

Conjugate

Unconjugated

Product Size & Price

Product size: 500ug

Product price: $950

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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