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TNFSF11 : Osteoprotegerin Inhibitor Screening ELISA Kit

Product specifications

Receptor activator of nuclear factor kappa-B ligand (RANKL), also known as tumor necrosis factor ligand superfamily member 11 (TNFSF11), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is known as a type II membrane protein and is a member of the tumor necrosis factor (TNF) superfamily. RANKL, through its ability to stimulate osteoclast formation and activity, is a critical mediator of bone resorption and overall bone density. Some findings also suggestion some cancer cells, particularly prostate cancer cells, can activate an increase in bone remodeling and ultimately increase overall bone production. This increase in bone remodeling and bone production increases the overall growth of bone metastasizes. The overall control of bone remodeling is regulated by the binding of RANKL with its receptor or its decoy receptor, respectively, RANK and OPG.

Catalog Number

EP-145

Product Category

Inhibitor Screening ELISA Kits

Storage Tempreture

2-8℃

Species

Human

Applications

This kit is developed for screening for inhibitors of human TNFSF11 binding to human Osteoprotegerin.

Product Size & Price

Product size: 96tests

Product price: $650

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Shipping condition & fees

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Shipping & Handling

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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