METAFECTENE® FluoR is designed for transient transfection of mammalian cell lines and primary cells with DNA (plasmids, bacmids). By the fluorescent label endocytosis of the cells can be analyzed under the fluorescence microscope. But it is also suitable for other nucleic acids like RNA (mRNA, miRNA, and siRNA), and modified nucleic acids (antisense oligonucleotides).
T050-1.0
The finding that lipofection is also attacked by the defense measures of the innate immune system led us to develop the K2® Transfection System, consisting of the K2® Transfection Reagent and the K2® Multiplier. The K2® Transfection Reagent is based on powerful cationic lipids (as liposomes), while the Multiplier decreases the cells’ ability to detect nucleic acids. The K2® Transfection System is therefore a further development of the transfection reagent METAFECTENE® PRO.
T060-0.75
The finding that lipofection is also attacked by the defense measures of the innate immune system led us to develop the K2® Transfection System, consisting of the K2® Transfection Reagent and the K2® Multiplier. The K2® Transfection Reagent is based on powerful cationic lipids (as liposomes), while the Multiplier decreases the cells’ ability to detect nucleic acids. The K2® Transfection System is therefore a further development of the transfection reagent METAFECTENE® PRO.
T060-1.0
The finding that lipofection is also attacked by the defense measures of the innate immune system led us to develop the K2® Transfection System, consisting of the K2® Transfection Reagent and the K2® Multiplier. The K2® Transfection Reagent is based on powerful cationic lipids (as liposomes), while the Multiplier decreases the cells’ ability to detect nucleic acids. The K2® Transfection System is therefore a further development of the transfection reagent METAFECTENE® PRO.
T060-2.0
The finding that lipofection is also attacked by the defense measures of the innate immune system led us to develop the K2® Transfection System, consisting of the K2® Transfection Reagent and the K2® Multiplier. The K2® Transfection Reagent is based on powerful cationic lipids (as liposomes), while the Multiplier decreases the cells’ ability to detect nucleic acids. The K2® Transfection System is therefore a further development of the transfection reagent METAFECTENE® PRO.
T060-5.0
The knowledge that virtually all transfection methods are affected of the defenses of the innate immune system led to the development of the K4® Transfection System consisting of the K4® Transfection Reagent and the K4® Multiplier. The K4® Transfection Reagent is based on powerful cationic lipids, whereas the K4® Multiplier decreases the cells´ ability to detect foreign nucleic acids. Especially hard to transfect cells often express endosomal or cytosolic sensors that can detect nucleic acids. In contrast to the K2® Multiplier, the K4® Multiplier as its further development inhibits both groups of sensors.
T080-1.0
The knowledge that virtually all transfection methods are affected of the defenses of the innate immune system led to the development of the K4® Transfection System consisting of the K4® Transfection Reagent and the K4® Multiplier. The K4® Transfection Reagent is based on powerful cationic lipids, whereas the K4® Multiplier decreases the cells´ ability to detect foreign nucleic acids. Especially hard to transfect cells often express endosomal or cytosolic sensors that can detect nucleic acids. In contrast to the K2® Multiplier, the K4® Multiplier as its further development inhibits both groups of sensors.
T080-2.0
The knowledge that virtually all transfection methods are affected of the defenses of the innate immune system led to the development of the K4® Transfection System consisting of the K4® Transfection Reagent and the K4® Multiplier. The K4® Transfection Reagent is based on powerful cationic lipids, whereas the K4® Multiplier decreases the cells´ ability to detect foreign nucleic acids. Especially hard to transfect cells often express endosomal or cytosolic sensors that can detect nucleic acids. In contrast to the K2® Multiplier, the K4® Multiplier as its further development inhibits both groups of sensors.
T080-5.0
The K4® multiplier is as additive to the cell culture medium easy to use and requires no optimization. It can therefore easily be combined with existing otimized transfection protocols. It is suitable for the transient and stable transfection of mammalian cell lines and also primary cells with DNA (plasmids, bacmids), RNA (mRNA, miRNA and siRNA) and modified nucleic acids (such as antisense oligonucleotides). Application areas are especially the production of proteins, antibodies and virus (E.g. AAV, adenovirus, lentivirus), cotransfectionens of various nucleic acids, genome editing (E.g. CRISPR/Cas9, CRISPR/Cpf1) and gene silencing (gene knockdown).
T082-1.0
The K4® multiplier is as additive to the cell culture medium easy to use and requires no optimization. It can therefore easily be combined with existing otimized transfection protocols. It is suitable for the transient and stable transfection of mammalian cell lines and also primary cells with DNA (plasmids, bacmids), RNA (mRNA, miRNA and siRNA) and modified nucleic acids (such as antisense oligonucleotides). Application areas are especially the production of proteins, antibodies and virus (E.g. AAV, adenovirus, lentivirus), cotransfectionens of various nucleic acids, genome editing (E.g. CRISPR/Cas9, CRISPR/Cpf1) and gene silencing (gene knockdown).
T082-2.0
