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Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (Monomer, MALS verified)

Product specifications

Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein (HLW-H82E5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 – Thr 305 (HLA-A*02:01) & Ile 21 – Met 119 (B2M) & RMFPNAPYL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & RMFPNAPYL).

Biotinylated Human HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Complex Protein is produced by co-expression of HLA and B2M loaded with WT-1 peptide.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 36.0 kDa and 13.9 kDa. The protein migrates as 42-45 kDa and 14 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

HLW-H82E5-200ug

Product Category

Proteins & Peptides

Material Category

MABSol® Biotin Labeled Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

MABSol® Biotin Labeled Proteins

Format

Powder

Purity

95%

Conjugate

Biotin-labeled

Bioactivity

Wilms tumor gene 1 (WT1),is an attractive target antigen for leukemia and solid cancer. WT1-specific adoptive immunotherapy has developed for tumor treatment in recent years. WT1 has been proved wildly expressed in breast, colon and ovarian cancer. It participates in cell growth, differentiation and apoptosis regulation. The WT1127-134 (RMFPNAPYL) was shown to be recognized by HLA-A*0201 tumor-infiltrating lymphocytes from melanoma patients, and therefore it is widely been studied in TCR-T studies. The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.

Molecule

HLA-A*02:01 & B2M & WT-1

Tag

C-10×His & C-Avi

Expression System

HEK293

Expregion

Gly 25 - Thr 305 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & RMFPNAPYL peptide

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 200ug

Product price: 680

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Order Details

We are continuously updating our catalog with advanced verified products. please send your request of our latest COA&SDS datasheet

Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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