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Biotinylated Human PD-L1 / B7-H1 Protein, Fc,Avitag™,His Tag (MALS verified)

Product specifications

Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.

This protein carries a human IgG1 Fc fragment at the C-terminus, followed by a polyhistidine tag. The Avi tag (Avitag™) is inserted in-between the Fc and his tags. The protein has a calculated MW of 54.0 kDa. The protein migrates as 65-80 kDa on a SDS-PAGE gel when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition due to glycosylation.

Catalog Number

PD1-H82F3-25ug

Product Category

Proteins & Peptides

Material Category

MABSol® Biotin Labeled Proteins

Supplier

ACROBiosystems

Species

Human

Host

HEK293

Format

Powder

Purity

95%

Conjugate

Biotin-labeled

Source

Biotinylated Human PD-L1, Fc,Avitag,His Tag (PD1-H82F3) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Arg 238 (Accession # NP_054862.1).

Molecule

PD-L1

Tag

C-Fc & C-Avi & C-6×His

Expregion

Phe 19 - Arg 238

Endotoxin Level

1.0 EU per μg

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Product Size & Price

Product size: 25ug

Product price: 385

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Order Details

We are continuously updating our catalog with advanced verified products. please send your request of our latest COA&SDS datasheet

Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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