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Biotinylated Human PD-L2 / B7-DC Protein, Avitag™,His Tag (recommended for biopanning)

Product specifications

Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.

This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.2 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

PD2-H82E8-200ug

Product Category

Proteins & Peptides

Material Category

MABSol® Biotin Labeled Proteins

Supplier

ACROBiosystems

Species

Human

Host

HEK293

Format

Powder

Purity

95%

Conjugate

Biotin-labeled

Source

Biotinylated Human PD-L2, Avitag,His Tag (PD2-H82E8) is expressed from human 293 cells (HEK293). It contains AA Leu 20 - Pro 219 (Accession # AAI13679).

Molecule

PD-L2

Tag

C-Avi & C-6×His

Expregion

Leu 20 - Pro 219

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 200ug

Product price: 1520

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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