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Biotinylated Human Siglec-15 / CD33L3 Protein, His,Avitag™ (recommended for biopanning)

Product specifications

Biotinylated Human Siglec-15 Protein, His,Avitag (SG5-H82E9) is expressed from human 293 cells (HEK293). It contains AA Phe 20 – Thr 263 (Accession # Q6ZMC9-1).

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 30.1 kDa. The protein migrates as 33-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

SG5-H82E9-25ug

Product Category

Proteins & Peptides

Material Category

MABSol® Biotin Labeled Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

MABSol® Biotin Labeled Proteins

Format

Powder

Purity

90%

Conjugate

Biotin-labeled

Bioactivity

Siglec-15 is a DAP12-associated immunoreceptor, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. Siglecs are cell surface proteins that bind sialic acid. They are found primarily on the surface of immune cells and are a subset of the I-type lectins. Siglec-15 consisting of immunoglobulin (Ig)-like domains, transmembrane domain and a short cytoplasmic tail. Siglec-15 is that recognizes sialylated glycans and regulates osteoclast differentiation. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates.

Molecule

Siglec-15

Tag

C-10×His & C-Avi

Expression System

HEK293

Expregion

Phe 20 - Thr 263

Endotoxin Level

1.0 EU per μg

Buffer

25 mM MES,150 mM NaCl, pH5.5

Product Size & Price

Product size: 25ug

Product price: 350

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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