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Biotinylated SARS-CoV-2 Spike NTD Protein (T19R, G142D, EF156-157del, R158G), His,Avitag™

Product specifications

Biotinylated SARS-CoV-2 Spike NTD, His,Avitag (SPD-C82H3) is expressed from human 293 cells (HEK293). It contains AA Ser 13 – Leu 303 (Accession # QHD43416.1 (T19R, G142D, EF156-157del, R158G)). The mutations T19R, G142D, EF156-157del, R158G were identified in the SARS-CoV-2 Delta variant (Pango lineage: B.1.617.2).

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.3 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

SPD-C82H3-200ug

Product Category

Proteins & Peptides

Material Category

MABSol® Biotin Labeled Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

SARS-CoV-2

Host

HEK293

Product Type

MABSol® Biotin Labeled Proteins

Format

Powder

Purity

95%

Conjugate

Biotin-labeled

Bioactivity

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molecule

Spike NTD

Tag

C-10×His & C-Avi

Expression System

HEK293

Expregion

Ser 13 - Leu 303

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 200ug

Product price: 1200

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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