Product specifications

Cynomolgus CD79B, His Tag (CDB-C52H3) is expressed from human 293 cells (HEK293). It contains AA Ala 30 – Asp 161 (Accession # A0A2K5WTH8-1).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 17.2 kDa. The protein migrates as 27-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

CDB-C52H3-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Cynomolgus

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

90%

Conjugate

Unconjugated

Bioactivity

B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.

Molecule

CD79B

Tag

C-10×His

Expression System

HEK293

Expregion

Ala 30 - Asp 161

Endotoxin Level

1.0 EU per μg

Buffer

PBS, 0.2 M Arginine, pH7.4

Product Size & Price

Product size: 1mg

Product price: 2540

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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