Product specifications

FITC-Labeled Human LILR84, Fc Tag (LI4-HF254) is expressed from human 293 cells (HEK293). It contains AA Gln 22 – Glu 259 (Accession # AAH26309.1).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 52.9 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

LI4-HF254-25ug

Product Category

Proteins & Peptides

Material Category

Fluorescent labeled protein

Supplier

ACROBiosystems

Storage Tempreture

-20℃, aviod light

Species

Human

Host

HEK293

Product Type

Fluorescent labeled protein

Format

Powder

Purity

90%

Conjugate

FITC Labeled

Bioactivity

Leukocyte immunoglobulin-like receptor subfamily B member 4 (LILRB4) is also known as CD85 antigen-like family member K (CD85K), Immunoglobulin-like transcript 3 (ILT-3), Leukocyte immunoglobulin-like receptor 5 (LIR-5), Monocyte inhibitory receptor HM18, which belongs to the leukocyte immunoglobulin-like receptor (LIR) family. LILRB4 / CD85K contains 2 Ig-like C2-type (immunoglobulin-like) domains. CD85K is detected in monocytes, macrophages, dendritic cells, lung, natural killer cells and B-cells. LILRB4 / CD85K is receptor for class I MHC antigens. CD85K recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles, involved in the down-regulation of the immune response and the development of tolerance. LILRB4 interferes with TNFRSF5-signaling and NF-kappa-B up-regulation and inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

Molecule

LILRB4

Tag

C-Fc

Expression System

HEK293

Expregion

Gln 22 - Glu 259

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 25ug

Product price: 319

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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