Product specifications

FITC-Labeled Human NCAM-1, Fc Tag (NC1-HF256) is expressed from human 293 cells (HEK293). It contains AA Leu 20 – Gly 718 (Accession # P13591-2).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 104.0 kDa. The protein migrates as 125-150 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

NC1-HF256-25ug

Product Category

Proteins & Peptides

Material Category

Fluorescent labeled protein

Supplier

ACROBiosystems

Storage Tempreture

-20℃, aviod light

Species

Human

Host

HEK293

Product Type

Fluorescent labeled protein

Format

Powder

Purity

90%

Conjugate

FITC Labeled

Bioactivity

NCAM1 belongs to the immunoglobulin superfamily of adhesion molecules. A wide range of alternatively spliced NCAM1 messenger RNAs (mRNAs) has been described to date, but only the 120-, 140-, and 180- kDa isoforms are commonly expressed. NCAM1 plays an important role in the regulation of neurogenesis, neurite outgrowth, proliferation, and cell migration, however, its function in hematopoiesis, including NK cells, is poorly understood. NCAM1 signaling is mediated either by homophilic or heterophilic interactions with fibroblast growth factor receptor (FGFR), L1-CAM, N-cadherin and other components of the extracellular matrix. Upon activation, NCAM1 triggers a variety of signaling cascades including FYN–focal adhesion kinase (FAK), MAPK, and phosphatidylinositol 3-kinase (PI3K) pathways.

Molecule

NCAM-1

Tag

C-Fc

Expression System

HEK293

Expregion

Leu 20 - Gly 718

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 25ug

Product price: 319

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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