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HCMV (strain Merlin) Glycoprotein B (gB), His Tag (MALS verified)

Product specifications

HCMV (strain Merlin) Glycoprotein B (gB), His Tag (CMB-V52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 25 – Glu 698 (Accession # F5HB53-1 (I156H, H157R, W240N, Y242T, C246S, R457S, R460S)).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 78.7 kDa. The protein migrates as 105-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

CMB-V52H5-500ug

Product Category

Proteins & Peptides

Material Category

Viral Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

HCMV

Host

HEK293

Product Type

Viral Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Human cytomegalovirus is a species of the Cytomegalovirus genus of viruses, which in turn is a member of the viral family known as Herpesviridae or herpesviruses. It is typically abbreviated as HCMV or, commonly but more ambiguously, as CMV. CMV Virus Envelope Glycoportein B (CMV-GB) can be cleaved into glycoprotein GP55. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. CMV-GB may be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Furthermore, CMV-GB can interact with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also, CMV-GB participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.

Molecule

Glycoprotein B / gB

Tag

C-10×His

Expression System

HEK293

Expregion

Ser 25 - Glu 698

Endotoxin Level

1.0 EU per μg

Buffer

PBS, 0.2 M Arginine, pH7.4

Product Size & Price

Product size: 500ug

Product price: 1760

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Order Details

We are continuously updating our catalog with advanced verified products. please send your request of our latest COA&SDS datasheet

Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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