Product specifications

Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 110.0 kDa. The protein migrates as 125-150 kDa under reducing (R) condition, and 250-300 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Catalog Number

AC2-H5255-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Species

Human

Host

HEK293

Format

Liquid

Purity

95%

Conjugate

Unconjugated

Source

Human ACE2, Fc Tag (AC2-H5255) is expressed from human 293 cells (HEK293).

Molecule

ACE2

Tag

C-Fc

Expregion

N/A

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 1mg

Product price: 3080

Add to quote

Shipping condition & fees

All prices are exclusive of duties, taxes, customs & Shipping fees

Shipping & Handling

Our customer service will inform you about the expected delivery time.

Order Details

We are continuously updating our catalog with advanced verified products. please send your request of our latest COA&SDS datasheet

Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

Get a quote