Product specifications

Human Activin A, premium grade (ACA-H421b) is expressed from human 293 cells (HEK293). It contains AA Gly 311 – Ser 426 (Accession # AAH07858.1).

This protein carries no “tag”. The protein has a calculated MW of 13.0 kDa. The protein migrates as 14-15 kDa under reducing (R) condition, and 23-25 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Catalog Number

ACA-H421b-100ug

Product Category

Proteins & Peptides

Material Category

ActiveMax® Cytokines

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

ActiveMax® Cytokines

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely inhibin down regulates FSH synthesis and inhibits FSH secretion.Activins are nonglycosylated homodimers or heterodimers of various β subunits (βA, βB, βC, and βE in mammals), while Inhibins are heterodimers of a unique α subunit and one of the β subunits. Activin A is a widely expressed homodimer of two βA chains. The βA subunit can also heterodimerize with a βB or βC subunit to form Activin AB and Activin AC, respectively. The 14 kDa mature human βA chain shares 100% amino acid sequence identity with bovine, feline, mouse, porcine, and rat βA.

Molecule

Activin A

Tag

Native

Expression System

HEK293

Expregion

Gly 311 - Ser 426

Endotoxin Level

0.1 EU per μg

Buffer

0.056% TFA in 30% ACN

Product Size & Price

Product size: 100ug

Product price: 650

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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