Product specifications

Disintegrin and metalloproteinase domain-containing protein 8 is also known as ADAM8, Cell surface antigen MS2 and CD antigen CD156a, which belongs to the ADAM (a disintegrin and metalloprotease domain) family. ADAM family play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. ADAM8 / CD156a contains 1 disintegrin domain, 1 EGF-like domain and 1 peptidase M12B domain. ADAM8 / MS2 / CD156a is expressed on neutrophils and monocytes. ADAM8 / MS2 possible involvement in extravasation of leukocytes.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.8 kDa. Two main fragments bands are visible with apparent MW of 57-65 kDa and 35-40 kDa respectively in reduced SDS-PAGE as a result of its being prone to proteolytic cleavage.

Catalog Number

AD8-H5223-50ug

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Species

Human

Host

HEK293

Format

Powder

Purity

90%

Conjugate

Unconjugated

Source

Human ADAM8, His Tag (AD8-H5223) is expressed from human 293 cells (HEK293). It contains AA Ile 17 - Pro 497 (Accession # AAI15405.1).

Molecule

ADAM8

Tag

C-6×His

Expregion

Ile 17 - Pro 497

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Product Size & Price

Product size: 50ug

Product price: 290

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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