Product specifications

Human Abeta40, His Tag (APP-H51H7) is expressed from E. coli cells. It contains AA Asp 672 – Val 711 (Accession # P05067-1).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 6.3 kDa. The protein migrates as 11 kDa under reducing (R) condition (SDS-PAGE).

Catalog Number

APP-H51H7-100ug

Product Category

Proteins & Peptides

Material Category

Other Recombinant Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

E. coli

Product Type

Other Recombinant Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. It has three predominant splice variants: APP695, APP751, and APP770. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain, releasing sAPPβ from a membrane-anchored fragment named βCTF or C99, which is subsequently cleaved by γ-secretase to release Aβ.

Molecule

APP

Tag

C-10×His

Expression System

E. coli

Expregion

Asp 672 - Val 711

Endotoxin Level

1.0 EU per μg

Buffer

PBS, 0.2 M Arginine, pH7.4

Product Size & Price

Product size: 100ug

Product price: 380

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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