Human BCMA / TNFRSF17 Protein, Fc Tag, premium grade
Product specifications
Human BCMA, Fc Tag (HPLC verified) (BC7-H5254) is expressed from human 293 cells (HEK293). It contains AA Met 1 – Ala 54 (Accession # NP_001183.2).
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.0 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Catalog Number
BC7-H5254-1mg
Product Category
Proteins & Peptides
Material Category
Bio-Markers & CD Antigens
Supplier
ACROBiosystems
Storage Tempreture
-20℃
Species
Human
Host
HEK293
Product Type
Bio-Markers & CD Antigens
Format
Powder
Purity
95%
Conjugate
Unconjugated
Bioactivity
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Molecule
BCMA
Tag
C-Fc
Expression System
HEK293
Expregion
Met 1 - Ala 54
Endotoxin Level
0.01 EU per μg
Buffer
PBS, pH7.4
