Product specifications

Human CD155, His Tag (CD5-H5223) is expressed from human 293 cells (HEK293). It contains AA Trp 21 – Asn 343 (Accession # NP_006496.4).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 35.9 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

CD5-H5223-100ug

Product Category

Proteins & Peptides

Material Category

Immune Checkpoint Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Immune Checkpoint Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155/PVR was originally isolated based on its ability to mediate polio virus attachment to host cells. The fulllength (or CD155 alpha isoform) is synthesized as a 417 amino acid (aa) precursor that contains a 20 aa signal sequence, a 323 aa extracellular region, a 24 aa TM segment and a 50 aa cytoplasmic tail. The extracellular region contains one N terminal V type and two C2 type Ig like domains. CD155 is a transmembrane protein with 3 extracellular immunoglobulin-like domains, D1-D3, where D1 is recognized by the virus. Low resolution structures of CD155 complexed with poliovirus have been obtained using electron microscopy while a high resolution structures of theectodomain D1 and D2 of CD155 were solved by x-ray crystallography.

Molecule

CD155

Tag

C-6×His

Expression System

HEK293

Expregion

Trp 21 - Asn 343

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 100ug

Product price: 273

Add to quote

Shipping condition & fees

All prices are exclusive of duties, taxes, customs & Shipping fees

Shipping & Handling

Our customer service will inform you about the expected delivery time.

Order Details

We are continuously updating our catalog with advanced verified products. please send your request of our latest COA&SDS datasheet

Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

Get a quote