Product specifications

Human CD45, His Tag (CD5-H52H8) is expressed from human 293 cells (HEK293). It contains AA Gln 26 – Lys 577 (Accession # P08575-3).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.8 kDa. The protein migrates as 120-170 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

CD5-H52H8-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

90%

Conjugate

Unconjugated

Bioactivity

CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

Molecule

CD45

Tag

C-10×His

Expression System

HEK293

Expregion

Gln 26 - Lys 577

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 1mg

Product price: 2540

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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