Product specifications

Human CD58, Fc Tag (LF3-H5256) is expressed from human 293 cells (HEK293). It contains AA Phe 29 – Arg 215 (Accession # AAH05930).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.1 kDa. The protein migrates as 60-70 kDa under reducing (R) condition, and 150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to different glycosylation.

Catalog Number

LF3-H5256-100ug

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) [3] on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

Molecule

CD58

Tag

C-Fc

Expression System

HEK293

Expregion

Phe 29 - Arg 215

Endotoxin Level

1.0 EU per μg

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Product Size & Price

Product size: 100ug

Product price: 280

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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