Product specifications

Human CD8 alpha, His Tag (CDA-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 22 – Asp 182 (Accession # P01732-1).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.5 kDa. The protein migrates as 26-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

CDA-H52H3-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

Molecule

CD8 alpha

Tag

C-10×His

Expression System

HEK293

Expregion

Ser 22 - Asp 182

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 1mg

Product price: 2860

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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