Product specifications

Human DLL1, His Tag (DL1-H52H8) is expressed from human 293 cells (HEK293). It contains AA Gln 18 – Gly 540 (Accession # NP_005609).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.4 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

DL1-H52H8-1mg

Product Category

Proteins & Peptides

Material Category

Other Recombinant Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Other Recombinant Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.

Molecule

DLL1

Tag

C-10×His

Expression System

HEK293

Expregion

Gln 18 - Gly 540

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 150 mM NaCl, pH 7.5

Product Size & Price

Product size: 1mg

Product price: 1760

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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