Product specifications

Human EMMPRIN, Fc Tag (CD7-H5259) is expressed from human 293 cells (HEK293). It contains AA Ala 22 – His 205 (Accession # NP_940991.1).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 46.3 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

CD7-H5259-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

Molecule

EMMPRIN

Tag

C-Fc

Expression System

HEK293

Expregion

Ala 22 - His 205

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 100 mM Glycine, pH7.5

Product Size & Price

Product size: 1mg

Product price: 1600

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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