Product specifications

Human KIR3DL3, Fc Tag (KI3-H5259) is expressed from human 293 cells (HEK293). It contains AA Gln 26 – Leu 322 (Accession # Q8N743-1).

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 58.7 kDa. The protein migrates as 66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

KI3-H5259-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

the inhibitory KIR surface receptors possessing three extracellular immunoglobin (Ig) domains (3D) and only one inhibitory motif within the long cytoplasmic domain (L) due to a premature stop codon. Moreover, exon 6 of KIR3DL3 encoding the stem part of the receptor is also absent, which differs from other inhibitory KIRs. Understanding the function of KIR3DL3 is further complicated by the unknown identity of the specific ligand, but its importance is highlighted by its presence in all human KIR haplotypes with 120 distinct polymorphic alleles of the coding sequence [

Molecule

KIR3DL3

Tag

C-Fc

Expression System

HEK293

Expregion

Gln 26 - Leu 322

Endotoxin Level

1.0 EU per μg

Buffer

51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5

Product Size & Price

Product size: 1mg

Product price: 2540

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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