Product specifications

Human LRRC4, His Tag (LR4-H5221) is expressed from human 293 cells (HEK293). It contains AA Ala 39 – Lys 527 (Accession # AAI11562.1).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.8 kDa. The protein migrates as 90-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

LR4-H5221-100ug

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

92%

Conjugate

Unconjugated

Bioactivity

LRRC4 (Leu-rich repeat/LRR-containing glycoprotein 4), LRRC4B and LRRC4C are post-synaptic adhesion molecules of the LRR protein family that induce excitatory synapse formation. LRRC4 is also known as Brain tumor-associated protein BAG, Netrin-G2 ligand (NGL-2), Nasopharyngeal carcinoma-associated gene 14 protein (NAG14), which contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats, 1 LRRCT domain, 1 LRRNT domain. LRRC4 / NGL-2 specifically expressed in brain. LRRC4 / NGL-2 regulates the formation of exitatory synapses through the recruitment of pre-and-postsynaptic proteins. LRRC4 / NGL-2 organize the lamina/pathway-specific differentiation of dendrites. LRRC4 / NGL-2 plays a important role for auditory synaptic responses and involved in the suppression of glioma.

Molecule

LRRC4

Tag

C-6×His

Expression System

HEK293

Expregion

Ala 39 - Lys 527

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 100ug

Product price: 290

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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