Product specifications

Human Lumican, His Tag (LUM-H5227) is expressed from human 293 cells (HEK293). It contains AA Gln 19 – Asn 338 (Accession # NP_002336).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.5 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

LUM-H5227-1mg

Product Category

Proteins & Peptides

Material Category

Other Recombinant Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Other Recombinant Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Lumican (LUM) is also known as Keratan sulfate proteoglycan lumican, KSPG lumican,LDC and SLRR2D, which belongs to the small leucine-rich proteoglycan (SLRP) family and SLRP class II subfamily. LUM /Lumican is present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage LUM /Lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan. LUM participates in the maintenance of tissue homeostasis and modulates cellular functions including cell proliferation, migration, and differentiation. The expression of LUM has been correlated to the growth and metastasis of various malignancies.

Molecule

Lumican

Tag

C-6×His

Expression System

HEK293

Expregion

Gln 19 - Asn 338

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.4

Product Size & Price

Product size: 1mg

Product price: 1760

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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