Product specifications

Human S100B, His Tag (S1B-H5143) is expressed from E. coli cells. It contains AA Ser 2 – Glu 92 (Accession # NP_006263).

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 11.5 kDa. The protein migrates as 11 kDa under reducing (R) condition (SDS-PAGE).

Catalog Number

S1B-H5143-1mg

Product Category

Proteins & Peptides

Material Category

Other Recombinant Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

E. coli

Product Type

Other Recombinant Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

S-100 protein beta chain (S100B),a member of the S-100 family, is also known as S-100 protein subunit beta and S100 calcium-binding protein B, which contains two EF-hand domains. S100B can weakly bind calcium but bind zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Also, S100B can bind to and initiate the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction,S100B may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Fuethermore,S100B could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. S100B may mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

Molecule

S100B

Tag

N-6×His

Expression System

E. coli

Expregion

Ser 2 - Glu 92

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 150 mM NaCl, pH8.0

Product Size & Price

Product size: 1mg

Product price: 1430

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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