Product specifications

Human Serpin D1, His Tag (HC2-H5224) is expressed from human 293 cells (HEK293). It contains AA Gly 20 – Ser 499 (Accession # AAH35028).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 55.7 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

HC2-H5224-1mg

Product Category

Proteins & Peptides

Material Category

Other Recombinant Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Human

Host

HEK293

Product Type

Other Recombinant Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

Serpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 / HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 / HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.

Molecule

Serpin D1

Tag

C-6×His

Expression System

HEK293

Expregion

Gly 20 - Ser 499

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 150 mM NaCl, pH 7.5

Product Size & Price

Product size: 1mg

Product price: 1980

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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