Product specifications

Angiotensin-converting enzyme 2 (ACE2) is also known as ACEH (ACE homolog), is an integral membrane protein with considerable homologous to ACE, which belongs to the peptidase M2 family. ACE2 is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin, or the conversion of angiotensin II to angiotensin 1-7. ACE2 may be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, ACE-2 serve as functional receptor for the spike glycoprotein of both coronaviruses. ACE2 is activated by chloride and fluoride, but not bromide and Inhibited by MLN-4760, cFP_Leu, and EDTA, but not by the ACE inhibitors linosipril, captopril and enalaprilat. ACE2 is active from pH 6 to 9, and the optimum pH is 6.5 in the presence of 1 M NaCl.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 86.3 kDa. The protein migrates as 95-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

AC2-M52H3-1mg

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Species

Mink

Host

HEK293

Format

Powder

Purity

95%

Conjugate

Unconjugated

Source

Mink ACE2, His Tag (AC2-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Thr 740 (Accession # QPL12211.1).

Molecule

ACE2

Tag

C-10×His

Expregion

Gln 18 - Thr 740

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 150 mM Nacl, pH7.5

Product Size & Price

Product size: 1mg

Product price: 3080

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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