Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa , multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A30L is a Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 16.0 kDa. The protein migrates as 25-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Proteins & Peptides
Monkeypox virus (strain Zaire-96-I-16)
Monkeypox virus (strain Zaire-96-I-16) A30L, His Tag (A3L-M5243) is expressed from human 293 cells (HEK293). It contains AA Ser 22 - Leu 146 (Accession # Q8V4U9-1).
Ser 22 - Leu 146
1.0 EU per μg