Product specifications

Mouse IgG2a Fc, Tag Free (IGA-M5207) is expressed from human 293 cells (HEK293). It contains AA Glu 98 – Lys 330 (Accession # CAC20702).

This protein carries no “tag”. The protein has a calculated MW of 26.4 kDa. The protein migrates as 30-35 kDa under reducing (R) condition, and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Catalog Number

IGA-M5207-200ug

Product Category

Proteins & Peptides

Material Category

Other Recombinant Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Mouse

Host

HEK293

Product Type

Other Recombinant Proteins

Format

Powder

Purity

90%

Conjugate

Unconjugated

Bioactivity

Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.

Molecule

IgG2a Fc

Tag

Native

Expression System

HEK293

Expregion

Glu 98 - Lys 330

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5

Product Size & Price

Product size: 200ug

Product price: 270

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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