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Mouse Integrin alpha 1 beta 1 (ITGA1&ITGB1) Heterodimer Protein, His Tag&Tag Free

Product specifications

Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-M52W6) is expressed from human 293 cells (HEK293). It contains AA Phe 29 – Pro 1141 (ITGA1) & Gln 21 – Asp 728 (ITGB1) (Accession # Q3V3R4-1 (ITGA1) & P09055-1 (ITGB1)).

Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA1 and ITGB1, has a calculated MW of 130.0 kDa (ITGA1) and 83.5 kDa (ITGB1). Subunit ITGA1 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The reducing (R) protein migrates as 150-200 kDa (ITGA1) and 90-130 kDa (ITGB1) respectively due to glycosylation.

Catalog Number

IT1-M52W6-100ug

Product Category

Proteins & Peptides

Material Category

Bio-Markers & CD Antigens

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

Mouse

Host

HEK293

Product Type

Bio-Markers & CD Antigens

Format

Powder

Purity

90%

Conjugate

Unconjugated

Bioactivity

Integrin alpha-1/beta-1 is a receptor for laminin and collagen. The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

Molecule

Integrin alpha 1 beta 1

Tag

C-10×His | Native

Expression System

HEK293

Expregion

Phe 29 - Pro 1141 (ITGA1) & Gln 21 - Asp 728 (ITGB1)

Endotoxin Level

1.0 EU per μg

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Product Size & Price

Product size: 100ug

Product price: 410

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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