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PE-Labeled Mouse SIRP alpha Protein, His Tag (Site-specific conjugation)

Product specifications

PE-Labeled Mouse SIRP alpha, His Tag (SIA-MP2H6) is produced via site-specific conjugation of PE to Mouse SIRP alpha, His Tag under optimal conditions with a proprietary technology. Mouse SIRP alpha, His Tag is expressed from human 293 cells (HEK293). It contains AA Lys 32 – Asn 373 (Accession # P97797-1).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 41.5 kDa.

Catalog Number

SIA-MP2H6-25tests

Product Category

Proteins & Peptides

Material Category

Fluorescent labeled protein

Supplier

ACROBiosystems

Storage Tempreture

-20℃, aviod light

Species

Mouse

Host

HEK293

Product Type

Fluorescent labeled protein

Format

Powder

Purity

N/A

Conjugate

PE Labeled

Bioactivity

Tyrosine-protein phosphatase non-receptor type substrate 1 (SHPS1) is also known as CD172 antigen-like family member A (CD172a), Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha (SIRPA or SIRP alpha) or p84, is a member of the SIRP family, and also belongs to the immunoglobulin superfamily. SIRP alpha is Ubiquitous and highly expressed in brain. SIRPA / CD172a is immunoglobulin-like cell surface receptor for CD47 and acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRPA / SHPS-1 supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment and may play a key role in intracellular signaling during synaptogenesis and in synaptic function By similarity. SIRPA / MyD1 involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin and mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells.

Molecule

SIRP alpha

Tag

C-10×His

Expression System

HEK293

Expregion

Lys 32 - Asn 373

Endotoxin Level

N/A

Buffer

PBS, 0.5% BSA, pH7.4

Product Size & Price

Product size: 25tests

Product price: 335

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Order Details

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Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

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