, , , , ,

SARS-CoV-2 Spike RBD Protein (K417N, L452R, T478K), His Tag (MALS verified)

Product specifications

SARS-CoV-2 Spike RBD (K417N, L452R, T478K), His Tag (SPD-C5226) is expressed from human 293 cells (HEK293). It contains AA Arg 319 – Lys 537 (Accession # QHD43416.1 (K417N, L452R, T478K)). The mutations K417N, L452R, T478K were identified in the SARS-CoV-2 Delta sub-lineages (Pango lineage: AY.1, AY.2, AY.3; also known as “Delta Plus”).

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.6 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Catalog Number

SPD-C5226-100ug

Product Category

Proteins & Peptides

Material Category

Viral Proteins

Supplier

ACROBiosystems

Storage Tempreture

-20℃

Species

SARS-CoV-2

Host

HEK293

Product Type

Viral Proteins

Format

Powder

Purity

95%

Conjugate

Unconjugated

Bioactivity

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Molecule

Spike RBD

Tag

C-10×His

Expression System

HEK293

Expregion

Arg 319 - Lys 537

Endotoxin Level

1.0 EU per μg

Buffer

PBS, pH7.3

Product Size & Price

Product size: 100ug

Product price: 360

Add to quote

Shipping condition & fees

All prices are exclusive of duties, taxes, customs & Shipping fees

Shipping & Handling

Our customer service will inform you about the expected delivery time.

Order Details

We are continuously updating our catalog with advanced verified products. please send your request of our latest COA&SDS datasheet

Limitations

Please note: All products are “FOR RESEARCH USE ONLY”. NOT FOR USE IN DIAGNOSTIC PROCEDURES or Human or Veterinary or Food.

Get a quote