Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag
Product specifications
Influenza A [Wisconsin/67/2022(H1N1)] Neuraminidase (NA) Protein, His Tag (NEE-V524m) is expressed from human 293 cells (HEK293). It contains AA Ser 31 – Asn 469 (Accession # EPI_ISL_15928538, GISAID).
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 56.4 kDa. The protein migrates as 55 kDa,65 kDa and 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Catalog Number
NEE-V524m-100ug
Product Category
Proteins & Peptides
Material Category
Viral Proteins
Supplier
ACROBiosystems
Storage Tempreture
-70℃
Species
Influenza
Host
HEK293
Product Type
Viral Proteins
Format
Liquid
Purity
90%
Conjugate
Unconjugated
Bioactivity
Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
Molecule
Neuraminidase (NA)
Tag
N-10×His
Expression System
HEK293
Expregion
Ser 31 - Asn 469
Endotoxin Level
1.0 EU per μg
Buffer
50 mM Tris, 300 mM NaCl, pH7.5
