Biotinylated Mouse PD-L2 / B7-DC Protein, His,Avitag™ (MALS verified)
Product specifications
Biotinylated Mouse PD-L2 Protein, His,Avitag (PD2-M82E3) is expressed from human 293 cells (HEK293). It contains AA Leu 20 – Arg 219 (Accession # Q9WUL5).
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 26.1 kDa. The protein migrates as 35-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Catalog Number
PD2-M82E3-200ug
Product Category
Proteins & Peptides
Material Category
MABSol® Biotin Labeled Proteins
Supplier
ACROBiosystems
Storage Tempreture
-20℃
Species
Mouse
Host
HEK293
Product Type
MABSol® Biotin Labeled Proteins
Format
Powder
Purity
90%
Conjugate
Biotin-labeled
Bioactivity
Programmed cell death 1 ligand 2 (PD-L2 or PDCD1 ligand 2) is also known as Butyrophilin B7-DC, CD antigen CD273, which belongs to the immunoglobulin superfamily or BTN/MOG family. The expression of PD-L2 is up-regulated by IFNG/IFN-gamma stimulation in monocytes and induced on dendritic cells grown from peripheral blood mononuclear cells with CSF2 and IL-4. PD-L2 Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PD-L2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Molecule
PD-L2
Tag
C-10×His & C-Avi
Expression System
HEK293
Expregion
Leu 20 - Arg 219
Endotoxin Level
1.0 EU per μg
Buffer
PBS, pH7.4
