Human Bcl-x / BCL2L1 Protein, GST Tag
Product specifications
Human Bcl-x, GST Tag (BC1-H513a) is expressed from E. coli cells. It contains AA Ser 2 – Arg 212 (Accession # AAH19307).
This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE).
Catalog Number
BC1-H513a-1mg
Product Category
Proteins & Peptides
Material Category
Bio-Markers & CD Antigens
Supplier
ACROBiosystems
Storage Tempreture
-20℃
Species
Human
Host
E. coli
Product Type
Bio-Markers & CD Antigens
Format
Powder
Purity
92%
Conjugate
Unconjugated
Bioactivity
Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
Molecule
Bcl-x
Tag
N-GST
Expression System
E. coli
Expregion
Ser 2 - Arg 212
Endotoxin Level
1.0 EU per μg
Buffer
20 mM Tris, 100 mM NaCl, pH7.5 with 10 mM GSH
