Human BCMA / TNFRSF17 Protein, Mouse IgG2a Fc Tag, low endotoxin
Product specifications
Human BCMA, Mouse IgG2a Fc Tag (BCA-H5253) is expressed from human 293 cells (HEK293). It contains AA Met 1 – Ala 54 (Accession # Q02223-1).
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 32.8 kDa. The protein migrates as 35-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Catalog Number
BCA-H5253-100ug
Product Category
Proteins & Peptides
Material Category
Bio-Markers & CD Antigens
Supplier
ACROBiosystems
Storage Tempreture
-20℃
Species
Human
Host
HEK293
Product Type
Bio-Markers & CD Antigens
Format
Powder
Purity
90%
Conjugate
Unconjugated
Bioactivity
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17) is also known as B-cell maturation protein (BCMA), CD antigen CD269, which is a member of the TNF-receptor superfamily. TNFRSF17 contains one TNFR-Cys repeat. TNFRSF17 is expressed in mature B-cells, but not in T-cells or monocytes. TNFRSF17 is receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B-cell survival and plays a role in the regulation of humoral immunity. TNFRSF17 can activate NF-kappa-B and JNK.
Molecule
BCMA
Tag
C-mFc(mIgG2a)
Expression System
HEK293
Expregion
Met 1 - Ala 54
Endotoxin Level
0.1 EU per μg
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
