Human Cathepsin D Protein, His Tag (active enzyme, MALS verified)
Product specifications
Human Cathepsin D Protein, His Tag (CAD-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 21 – Leu 412 (Accession # P07339-1).
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Catalog Number
CAD-H52H3-1mg
Product Category
Proteins & Peptides
Material Category
Enzymes
Supplier
ACROBiosystems
Storage Tempreture
-70℃
Species
Human
Host
HEK293
Product Type
Enzymes
Format
Liquid
Purity
95%
Conjugate
Unconjugated
Bioactivity
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Molecule
Cathepsin D
Tag
C-10×His
Expression System
HEK293
Expregion
Leu 21 - Leu 412
Endotoxin Level
1.0 EU per μg
Buffer
12.5 mM MES, 75 mM NaCl, pH6.5
